Novel immune scoring dynamic nomograms based on B7-H3, B7-H4, and HHLA2: Potential prediction in survival and immunotherapeutic efficacy for gallbladder cancer

BackgroundGallbladder cancer (GBC) is a mortal malignancy with limited therapeutic strategies.We aimed to develop novel immune scoring systems focusing on B7-H3, B7-H4, and HHLA2.We further investigated their potential clinical effects in predicting survival and immunotherapeutic efficacy for mezquila brooklyn GBC.MethodsThis was a retrospective co

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Improvement of machined accuracy under constant feed speed at milling point with a five axis controlled machining center considering approach path

We suggested a novel method to maintain a machined surface quality of a curved surface shape by synchronous motion between two linear axes and a rotary axis with the five-axis machining center.It was demonstrated that the proposed method made it feasible to prevent a machined error due to the quadrant glitch caused by friction of the ball screw and

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